The journey from a laboratory hypothesis to a pharmacy shelf is one of the most grueling marathons in modern industry, typically spanning 10 to 15 years and billions of dollars in investment.
Progress is often stymied not just by the inherent mysteries of biology, but by the “fragmented and difficult to scale” workflows that force researchers to manually pivot between the actual experimental design equipment, software, and databases.
But OpenAI is releasing a new specialized model GPT-Rosalind specifically to speed up this process and make it more efficient, easier, and ideally, more productive. Named after the pioneering chemist Rosalind Franklin, whose work was vital to the discovery of DNA’s structure (and was often overlooked for her male colleagues James Watson and Francis Crick), this new frontier reasoning model is purpose-built to act as a specialized intelligence layer for life sciences research.
By shifting AI’s role from a general-purpose assistant to a domain-specific “reasoning” partner, OpenAI is signaling a long-term commitment to biological and chemical discovery.
GPT-Rosalind isn’t just about faster text generation; it is designed to synthesize evidence, generate biological hypotheses, and plan experiments—tasks that have traditionally required years of expert human synthesis.
At its core, GPT-Rosalind is the first in a new series of models optimized for scientific workflows. While previous iterations of GPT excelled at general language tasks, this model is fine-tuned for deeper understanding across genomics, protein engineering, and chemistry.
To validate its capabilities, OpenAI tested the model against several industry benchmarks. On BixBench, a metric for real-world bioinformatics and data analysis, GPT-Rosalind achieved leading performance among models with published scores.
In more granular testing via LABBench2, the model outperformed GPT-5.4 on six out of eleven tasks, with the most significant gains appearing in CloningQA—a task requiring the end-to-end design of reagents for molecular cloning protocols.
The model’s most striking performance signal came from a partnership with Dyno Therapeutics. In an evaluation using unpublished, “uncontaminated” RNA sequences, GPT-Rosalind was tasked with sequence-to-function prediction and generation.
When evaluated directly in the Codex environment, the model’s submissions ranked above the 95th percentile of human experts on prediction tasks and reached the 84th percentile for sequence generation.
This level of expertise suggests the model can serve as a high-level collaborator capable of identifying “expert-relevant patterns” that generalist models often overlook.
OpenAI is not just releasing a model; it is launching an ecosystem designed to integrate with the tools scientists already use. Central to this is a new Life Sciences research plugin for Codex, available on GitHub.
Scientific research is famously siloed. A single project might require a researcher to consult a protein structure database, search through 20 years of clinical literature, and then use a separate tool for sequence manipulation. The new plugin acts as an “orchestration layer,” providing a unified starting point for these multi-step questions.
Skill Set: The package includes modular skills for biochemistry, human genetics, functional genomics, and clinical evidence.
Connectivity: It connects models to over 50 public multi-omics databases and literature sources.
Efficiency: This approach targets “long-horizon, tool-heavy scientific workflows,” allowing researchers to automate repeatable tasks like protein structure lookups and sequence searches.
Given the potential power of a model capable of redesigning biological structures, OpenAI is eschewing a broad “open-source” or general public release in favor of a Trusted Access program.
The model is launching as a research preview specifically for qualified Enterprise customers in the United States. This restricted deployment is built on three core principles: beneficial use, strong governance, and controlled access.
Organizations requesting access must undergo a qualification and safety review to ensure they are conducting legitimate research with a clear public benefit.
Unlike general-use models, GPT-Rosalind was developed with heightened enterprise-grade security controls. For the end-user, this means:
Restricted Access: Usage is limited to approved users within secure, well-managed environments.
Governance: Participating organizations must maintain strict misuse-prevention controls and agree to specific life sciences research preview terms.
Cost: During the preview phase, the model will not consume existing credits or tokens, allowing researchers to experiment without immediate budgetary constraints (subject to abuse guardrails).
The announcement garnered significant buy-in from OpenAI parnters across the pharmaceutical and technology sectors.
Sean Bruich, SVP of AI and Data at Amgen, noted that the collaboration allows the company to apply advanced tools in ways that could “accelerate how we deliver medicines to patients”.The impact is also being felt in the specialized tech infrastructure that supports labs:
NVIDIA: Kimberly Powell, VP of Healthcare and Life Sciences, described the convergence of domain reasoning and accelerated computing as a way to “compress years of traditional R&D into immediate, actionable scientific insights”.
Moderna: CEO Stéphane Bancel highlighted the model’s ability to “reason across complex biological evidence” to help teams translate insights into experimental workflows.
The Allen Institute: CTO Andy Hickl emphasized that GPT-Rosalind stands out for making manual steps—like finding and aligning data—more “consistent and repeatable in an agentic workflow”.
This builds on tangible results OpenAI has already seen in the field, such as its collaboration with Ginkgo Bioworks, where AI models helped achieve a 40% reduction in protein production costs.
OpenAI’s mission with GPT-Rosalind is to narrow the gap between a “promising scientific idea” and the actual “evidence, experiments, and decisions” required for medical progress.
By partnering with institutions like Los Alamos National Laboratory to explore AI-guided catalyst design and biological structure modification, the company is positioning GPT-Rosalind as more than a tool—it is meant to be a “capable partner in discovery”.
As the life sciences field becomes increasingly data-dense, the move toward specialized “reasoning” models like Rosalind may become the standard for navigating the “vast search spaces” of biology and chemistry.
Confirming it has reached 3 million weekly developers, OpenAI is massively updating its Codex developer environment via its Mac and Windows desktop apps today to bring it closer to the “Super App” the company has confirmed it is pursuing.
Before today, Codex was primarily an environment for using OpenAI’s underlying language models to write, edit, debug and ship software as directed by the user.
Now, Codex will be able to access all of the other apps on your computer, surface relevant information from within them to you when asked or proactively, take actions as directed in said applications, and, in the case of Mac users, even do so while you continue manually using your computer simultaneously to your agents working in the background.
Andrew Ambrosino, an OpenAI technical staffer on the Codex team, described the change plainly in an embargoed press briefing I attended virtually yesterday: “Codex can actually click on apps, launch apps, and type into apps. This works with any apps on your machine.”
Codex on desktop is further getting its own built-in web browser, allowing users to preview their front-end development, and a directly integrated pipeline to OpenAI’s powerful AI image generation model gpt-image-1.5, allowing users to generate imagery for their projects — everything from websites to presentations to full playable PC games with hundreds of assets — all in the same style.
As Thibault “Tibo” Sottiaux, Head of Codex at OpenAI, said during the briefing: “It’s not just about the growth. It is putting a very capable agent in the hands of builders, and now we’re seeing that we’re able to expand and do a lot more work entirely across your computer”
Asked why OpenAI was pursuing all this in Codex, not its more recognizable flagship app, ChatGPT, Sottiaux told VentureBeat: “Codex is our most powerful agent.It already worked on your computer, and so we’re expanding the capabilities there. It felt very natural. We will make it make sense at some point.”
The update comes as rival Anthropic has previously courted similar use cases with the launch of its Claude Cowork and redesigned Claude Code desktop app views, all available within the Claude desktop app for Mac and Windows. But Claude does not allow for simultaneous background app cursor usage from the desktop app across all of a user’s apps like Codex does.
The most significant technological leap in this release is “Computer Use,” limited for now to macOS users.
This feature allows Codex to break out of the traditional chatbot container to “see, click, and type” across all applications on a machine.
Crucially, this happens in the background. “It can use apps on your computer in the background, as opposed to taking over your entire computer,” explained Caffrey Lynch of OpenAI’s developer product communications.
This enables “multi-agent” workflows where Codex might be testing a frontend change or triaging a JIRA ticket while the developer continues working in a different application.
For Windows users, the core Codex desktop app remains available and supported — as does pulling information in from those apps to surface to the user in Codex — though it lacks the cursor-level background interaction available on Mac at launch.
Beyond operating the OS, OpenAI is doubling down on the “Software Development Lifecycle” (SDLC). The Codex app now functions more like a unified workspace, supporting everything from GitHub PR reviews to managing remote infrastructure.
“The simplest way to think about this release is teaching Codex and the app to work across a much larger surface area,” said Andrew Ambrosino, lead of Codex app development. This surface area now includes:
Integrated Browser: An in-app browser allows developers to iterate on frontend designs by commenting directly on DOM elements, providing precise instructions for the agent to follow.
Visual Primitives: By integrating gpt-image-1.5, Codex can now generate and iterate on images for mockups and game assets directly within the development workflow.
Expanded Sidebar: The app now includes rich previews for non-code files such as PDFs, spreadsheets, and slide decks, alongside a summary pane to track agent plans and sources.
Terminal & SSH: The update adds support for multiple terminal tabs and an alpha feature for connecting to remote devboxes via SSH.
To connect these disparate tasks, OpenAI is releasing more than 90 new plugins. These connectors—including CircleCI, GitLab, and Microsoft Suite—allow the agent to gather context and take action across the entire toolchain a developer uses daily.
In a demo video shown off during the briefing, OpenAI presented an example showing the user typing into the Codex prompt entry field, “Can you check Slack, Gmail, Google Calendar, and Notion and tell me what needs my attention?” showing how Codex can now scan across multiple apps and gather information from them all in single prompt, and surface what matters most to the user.
“You can @ mention them if you want Codex to use a specific app, or if not, Codex can discover which apps to use,” Ambrosino said.
One of the more subtle but powerful shifts is the introduction of persistent agency. Through “Heartbeat Automations,” Codex can now schedule future work for itself and “wake up” to continue long-term tasks.
This allows teams to set up agents that monitor Slack channels or Notion docs and proactively update documentation or landing PRs.
This is supported by a new “Memory” feature, currently in preview. Memory allows Codex to remember personal preferences, previous corrections, and gathered information, reducing the need for extensive custom instructions in every new session.
“As you use Codex, Codex also becomes better at being proactive,” noted Sottiaux.
This proactivity manifests in a “daily brief” style feature where the app suggests how to start the day by identifying open Google Doc comments or relevant Slack context.
It’s similar in spirit and practice to the new “Routines” feature launched by Anthropic for its Claude Code product earlier this week.
OpenAI has recently transitioned toward a more flexible pricing model for teams, including a $100 plan and pay-as-you-go options to accommodate the increased usage of autonomous agents. For individual users, these updates are rolling out today to those signed in to the Codex desktop app with ChatGPT.
While the Codex desktop app is available on both macOS and Windows, the rollout of specific features is tiered:
Background Computer Use: macOS only at launch.
Personalization (Memory/Suggestions): Coming soon for Enterprise, Edu, EU, and UK users.
Core Software Development Life Cycle Updates: Available to all desktop app users starting today.
When asked if these features represent the foundation of an AI “Super App,” Sottiaux confirmed the strategy: “We’re building the Super App in the open and evolving it out of the Codex app”.
The goal is to address the reality that developers spend a majority of their time on coordination and context-gathering rather than writing code.
By bringing Codex closer to the operating system and the broader ecosystem of developer tools, OpenAI is positioning it as the central nervous system for modern software development.
“Our mission is to ensure that AGI benefits all of humanity,” the company stated in its official announcement. “That means narrowing the gap between what people can imagine and what they can actually build”.
If we’re racing to build machines that are both more intelligent than we are and increasingly autonomomous, then we’re building agents that are functionally sovereign
Selection of Spielberg’s best films will be available in a strictly limited edition 4K Steelbook Library Case package.
Anthropic is publicly releasing its most powerful large language model yet, Claude Opus 4.7, today — as it continues to keep an even more powerful successor, Mythos, restricted to a small number of external enterprise partners for cybersecurity testing and patching vulnerabilities in the software said enterprises use (which Mythos exposed rapidly).
The big headlines are that Opus 4.7 exceeds its most direct rivals — OpenAI’s GPT-5.4, released in early March 2026, scarcely more than a month ago; and Google’s latest flagship model Gemini 3.1 Pro from February — on key benchmarks including agentic coding, scaled tool-use, agentic computer use, and financial analysis.
But also, it’s notable how tight the race is getting: on directly comparable benchmarks, Opus 4.7 only leads GPT-5.4 by 7-4.
It currently leads the market on the GDPVal-AA knowledge work evaluation with an Elo score of 1753, surpassing both GPT-5.4 (1674) and Gemini 3.1 Pro (1314).
Yet, the model does not represent a “clean sweep” across all categories.
Competitors like GPT-5.4 and Gemini 3.1 Pro still hold the lead in specific domains such as agentic search, where GPT-5.4 scores 89.3% compared to Opus 4.7’s 79.3%, as well as in multilingual Q&A and raw terminal-based coding.
This positioning defines Opus 4.7 not as a unilateral victor in all AI tasks, but as a specialized powerhouse optimized for the reliability and long-horizon autonomy required by the burgeoning agentic economy.
Claude Opus 4.7 is available today across all major cloud platforms, including Amazon Bedrock, Google Cloud’s Vertex AI, and Microsoft Foundry, with API pricing held steady at $5/$25 per million tokens.
Claude Opus 4.7 is a direct evolution of the Opus 4.6 architecture, but its performance delta is most visible in the “hard” sciences of agentic workflows: software engineering and complex document reasoning.
At its core, the model has been re-tuned to exhibit what Anthropic describes as “rigor”. This isn’t just marketing parlance; it refers to the model’s new ability to devise its own verification steps before reporting a task as complete.
For example, in internal tests, the model was observed building a Rust-based text-to-speech engine from scratch and then independently feeding its own generated audio through a separate speech recognizer to verify the output against a Python reference.
This level of autonomous self-correction is designed to reduce the “hallucination loops” that often plague earlier iterations of agentic software.
The most significant architectural upgrade is the move to high-resolution multimodal support. Opus 4.7 can now process images up to 2,576 pixels on their longest edge—roughly 3.75 megapixels.
This represents a three-fold increase in resolution compared to previous iterations. For developers building “computer-use” agents that must navigate dense, high-DPI interfaces or for analysts extracting data from intricate technical diagrams, this change effectively removes the “blurry vision” ceiling that previously limited autonomous navigation.
This visual acuity is reflected in benchmarks from XBOW, where the model jumped from a 54.5% success rate in visual-acuity tests to 98.5%.
On the benchmark front, Opus 4.7 has claimed the top spot in several critical categories:
Knowledge Work (GDPVal-AA): It achieved an Elo score of 1753, notably outperforming GPT-5.4 (1674) and Gemini 3.1 Pro (1314).
Agentic Coding (SWE-bench Pro): The model resolved 64.3% of tasks, compared to 53.4% for its predecessor.
Graduate-Level Reasoning (GPQA Diamond): It reached 94.2%, maintaining parity with the industry’s most advanced models while improving on its internal consistency.
Visual Reasoning (arXiv Reasoning): With tools, the model scored 91.0%, a meaningful jump from the 84.7% seen in Opus 4.6.
Crucially, Anthropic warns that this increased precision requires a shift in how users approach prompting. Opus 4.7 follows instructions literally. While older models might “read between the lines” and interpret ambiguous prompts loosely, Opus 4.7 executes the exact text provided. This means that legacy prompt libraries may require re-tuning to avoid unexpected results caused by the model’s strict adherence to the letter of the request.
The “agentic” nature of Opus 4.7—its tendency to pause, plan, and verify—comes with a trade-off in token consumption and latency.
To address this, Anthropic is introducing a new “effort” parameter. Users can now select an xhigh (extra high) effort level, positioned between high and max, allowing for more granular control over the depth of reasoning the model applies to a specific problem.
Internal data shows that while max effort yields the highest scores (approaching 75% on coding tasks), the xhigh setting provides a compelling sweet spot between performance and token expenditure.
To manage the costs associated with these more “thoughtful” runs, the Claude API is introducing “task budgets” in public beta. This allows developers to set a hard ceiling on token spend for autonomous agents, ensuring that a long-running debugging session doesn’t result in an unexpected bill.
These product changes signal a maturing market where AI is no longer a novelty but a production line item that requires fiscal and operational guardrails.
Furthermore, Opus 4.7 utilizes an updated tokenizer that improves text processing efficiency, though it can increase the token count of certain inputs by 1.0–1.35x.
Within the Claude Code environment, the update brings a new /ultrareview command. Unlike standard code reviews that look for syntax errors, /ultrareview is designed to simulate a senior human reviewer, flagging subtle design flaws and logic gaps.
Additionally, “auto mode”—a setting where Claude can make autonomous decisions without constant permission prompts—has been extended to Max plan users.
Anthropic continues to walk a narrow line regarding cybersecurity. The recent announcement of the aforementioend cybersecurity partnership around Mythos with external industry partners — known as “Project Glasswing” — highlighted the dual-use risks of high-capability models.
Consequently, while the flagship Mythos Preview model remains restricted, Opus 4.7 serves as the testbed for new automated safeguards. The model includes systems designed to detect and block requests that suggest high-risk cyberattacks, such as automated vulnerability exploitation.
To bridge the gap for the security industry, Anthropic is launching the Cyber Verification Program. This allows legitimate professionals—vulnerability researchers, penetration testers, and red-teamers—to apply for access to use Opus 4.7’s capabilities for defensive purposes.
This “verified user” model suggests a future where the most capable AI features are not universally available, but gated behind professional credentials and compliance frameworks.
In cybersecurity vulnerability reproduction (CyberGym), Opus 4.7 maintains a 73.1% success rate, trailing Mythos Preview’s 83.1% but leading GPT-5.4’s 66.3%.
Early testimonials from enterprise customers shared by Anthropic indicate there has been a tangible shift in model perception of Opus 4.7 from 4.6, going from “impressed by the tech” to “relying on the output”.
Clarence Huang, VP of Technology at Intuit, noted that the model’s ability to “catch its own logical faults during the planning phase” is a game-changer for velocity.
This sentiment was echoed by Replit President Michele Catasta, who stated that the model achieved higher quality at a lower cost for tasks like log analysis and bug hunting, adding, “It really feels like a better coworker”.
Other specific reactions included:
Cognition (Devin): CEO Scott Wu reported that Opus 4.7 can work coherently “for hours” and pushes through difficult problems that previously caused models to stall.
Notion: Sarah Sachs, AI Lead, highlighted a 14% improvement in multi-step workflows and a 66% reduction in tool-calling errors, making the agent feel like a “true teammate”.
Factory Droids: Leo Tchourakov observed that the model carries work through to validation steps rather than “stopping halfway,” a common complaint with previous frontier models.
Harvey: Niko Grupen, Head of Applied Research, noted the model’s 90.9% score on BigLaw Bench, highlighting its “noticeably smarter handling of ambiguous document editing tasks”.
Perhaps the most telling reaction came from Aj Orbach, CEO of a dashboard-building firm, who remarked on the model’s “design taste,” noting that its choices for data-rich interfaces were of a quality he would “actually ship”.
For enterprise leaders, Claude Opus 4.7 represents a shift from generative AI as a “creative assistant” to a “reliable operative.”
But importantly, it is not a “clean win” for every use case.
Instead, it is a decisive upgrade for teams building autonomous agents or complex software systems. The primary value proposition is the model’s new capability for self-verification and rigor; it no longer just generates an answer but creates internal tests to verify that the answer is correct before responding. This reliability makes it a superior choice for long-horizon engineering tasks where the cost of human supervision is the primary bottleneck.
However, an immediate, wholesale migration from Opus 4.6 requires caution. The model’s increased literalism in instruction following means that prompts engineered to be “loose” or conversational with previous versions may now produce unexpected or overly rigid results.
Furthermore, enterprises must prepare for a significant increase in operational costs. Opus 4.7 uses an updated tokenizer that can increase input token counts by 1.0–1.35x, and its tendency to “think harder” at high effort levels results in higher output token consumption.
For legacy applications where prompts are fragile and margins are thin, a phased rollout with significant re-tuning is recommended.
This release arrives at a paradoxical moment for Anthropic. Financially, the company is an undisputed juggernaut, with venture capital firms reportedly extending investment offers at a staggering $800 billion valuation—more than double its $380 billion Series G valuation from February 2026.
This momentum is fueled by explosive growth, with the company’s annual run-rate revenue skyrocketing to $30 billion in April 2026, driven largely by enterprise adoption and the success of Claude Code.
Yet, this commercial success is being contested by intense regulatory and technical friction. Anthropic is currently embroiled in a high-stakes legal battle with the U.S. Department of War (DoW), which recently labeled the company a “supply chain risk” after Anthropic refused to allow its models to be used for mass surveillance or fully autonomous lethal weapons.
While a San Francisco judge initially blocked the designation, a federal appeals panel recently denied Anthropic’s bid to stay the blacklisting, leaving the company excluded from lucrative defense contracts during an active military conflict.
Simultaneously, Anthropic is fending off a growing rebellion from its most loyal power users. Despite the company’s “market leader” status, developers have flooded GitHub and X with accusations of “AI shrinkflation,” claiming that the preceding Opus 4.6 model and Claude Code product have been quietly degraded.
Users report that recent versions are more prone to exploration loops, memory loss, and ignored instructions, leading some to describe the newly released Claude Code desktop app as “unpolished” and unbefitting a firm with a near-trillion-dollar valuation. Opus 4.7 is Anthropic’s attempt to silence these critics by proving that “deep thinking” can be paired with the rigorous execution that its enterprise clients now demand.
Ultimately, Opus 4.7 is a model defined by its discipline. In a market where models are often incentivized to be “helpful” to a fault—sometimes hallucinating answers to please the user—Opus 4.7 marks a return to rigor. By allowing users to control effort, set budgets, and verify outputs, Anthropic is moving closer to the goal of a truly autonomous digital labor force. For the engineering teams at Replit, Notion, and beyond, the shift from “watching the AI work” to “managing the AI’s results” has officially begun.
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